Controls to a virus that in Spain circulates “with out management”, does it make sense?: “The variants of China are already right here”


Scientists query covid controls on vacationers from China: “They cannot convey us something new” The variants circulating in China at the moment are the identical as in the remainder of the world: the BF.7 is the dominant one, and it has been round for a while Spain They do not forget that any extra harmful variant from another nation can attain us: “The drawback could come from the US.”

Covid controls to passengers coming from China. Health introduced it final Friday, and they’re already being executed. Spain requires destructive PCR or full vaccination schedule (vaccination passport) for vacationers from the Asian nation.

Do these controls make sense? From the scientific and epidemiological viewpoint, there isn’t a settlement. Some voices requested them, earlier than Health introduced them. But in the present day, there are various who think about that the measure doesn’t make any sense, because it has been carried out and on the present time of the pandemic. Neither to stop the entry of latest variants, nor as a result of the variants that will arrive from China are extra harmful than others.

Same virus, circulating uncontrollably

The microbiologist from the University of Navarra Ignacio López-Goñi has printed a thread on Twitter wherein he explains very clearly why these controls, in his opinion, don’t make sense. Starting with one thing very primary, that we’re not in the identical state of affairs that occurred in the beginning of the pandemic. “The virus is already right here and is circulating uncontrollably among the many inhabitants,” remembers the scientist.

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Why does not it make a lot sense to regulate the entry of Chinese passengers into airports?
So, what to do?
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1️⃣ The virus is already right here and is circulating uncontrollably among the many inhabitants.
2️⃣ In the EU there aren’t any borders between international locations, no specific measures make sense. pic.twitter.com/0rGXLAFMdh

— microBIO (@microBIOblog) January 1, 2023

Something comparable warns the immunologist Alfredo Corell, in statements to Informativos Telecinco. “In our inhabitants we now have already had the virus circulating freely and in excessive amount.” He considers that “the wise factor can be to request a PCR of 48 hours on the most, or to take an antigen check earlier than getting on the aircraft.” But not the vaccination passport, which, in his opinion, “must be eradicated as a management measure.”

In Spain, the containment measures have been relaxed for months now, the masks is voluntary, there aren’t any casualties because of covid and PCR is hardly carried out to observe the incidence of instances. The SARS-CoV-2 coronavirus circulates with out management inside our borders. And the virus that comes from China, as scientists warn, is identical one which circulates right here. We will not be speaking about one thing new.

New lineages in China?

The virus is continually evolving. And it continues to take action, in numerous components of the world, however since omicron arrived a yr in the past, every part remains to be omicron. In China, too.

There are an increasing number of lineages and sublineages of omicron that proliferate all through the planet. But up to now, none of these circulating in China have shocked scientists. “At this second they don’t have new, extra harmful variants. (Those who come) are going to convey the variants which might be already circulating right here,” Corell explains. “They cannot convey us something new.”

Manuel Muro, additionally an immunologist, agrees with Corell. On his Twitter profile he requires calm. “The variants in China are already in Spain. Even some like XBB sub-specializing in different international locations. We should not cease them, they’re already right here and competing with different earlier ones. Let’s not unfold psychosis the place there’s none.”

We know what circulates in China from the sequences that researchers from that nation have been sharing within the GISAID world database: they’re all comparable to those who flow into in the remainder of the world. This is what the veteran virologist and WHO adviser Marion Koopmans warns.

It have to be taken into consideration, sure, that the info that comes out of China should all the time be taken with warning. Because they sequence little, and since they share little. The sequencing knowledgeable from FISABIO Fernando González Candelas warned about it in NIUS a couple of days in the past. But from what has been reported up to now, all of them agree.

And López-Goñi warns the identical factor: “The wave of China appears to be dominated by sub-lineages that already flow into all through the planet.” In truth, the variant that dominates nearly all of infections in that nation is BF.7, a subvariant of omicron BA.5 that’s removed from new to us. “80% of what they’ve sequenced in China is BF.7, which is already in Spain and has not change into the bulk right here,” Corell remembers.

The BF.7 isn’t probably the most harmful

The BF.7 has been circulating in Spain for 4 months. If we have a look at the variant studies printed weekly by Health, we see that this variant was detected for the primary time on the finish of August. And since then, its evolution has been extremely variable, but it surely has not skyrocketed at any time. There are additionally a number of sublineages of the BF.7.

Nor does it appear that it’s the most evasive or the one which must be frightened probably the most. The knowledgeable in evolutionary biology T. Ryan Gregory warns it on Twitter. “BF.7 appears to be the primary variant rising in China in the meanwhile. It didn’t originate in China (extra doubtless Belgium). It has been circulating at low ranges outdoors of China since August. The XBB and BQ are far more worrisome. The worst (sub-variant), XBB.1.5, has developed within the US.”

Something comparable suggests López-Goñi. Why monitor solely the entry of vacationers from China if we are able to get new variants from anyplace on the earth? The scientist from Navarre agrees that probably the most harmful proper now (as a result of it’s transmissible, not as a result of it’s virulent) is the one that’s rising within the US. “The drawback could come from the US: the XBB.1.5 subvariant is surpassing the that dominated, BQ.1 and BQ.1.1, and in a couple of weeks it will likely be predominant”. BQ.1 and BQ.1.1. They are additionally those that at present dominate infections in Spain.

The scientist additionally factors to Japan, “which can be experiencing a rise in deaths from COVID19.” And he wonders: what will we do? Do we display screen vacationers from the US and Japan? And if the risk comes from one other nation? Variants can come up anyplace and at any time”, remembers the microbiologist.

González Candelas insisted on the identical. We do not know the place the following fear variant might be generated. And, in reality, he was saying, even whether it is generated in China, it can take time to be detected and probably not be detected in that nation. But it’s also true, he warns, that the better the variety of instances, the better the chance of continual infections in immunocompromised individuals, which is normally the perfect state of affairs for the virus to build up mutations and new variants to emerge.

As lengthy as that doesn’t occur (and if it does, it can take us some time to search out out), it doesn’t appear that BF.7 or any of these now circulating in China pose a brand new danger, even when they go away its borders.

Do unilateral controls work?

There is one more reason why many scientists stress that unilateral controls, solely in sure international locations, don’t make sense. “In the EU there aren’t any borders between international locations, there isn’t a sense particularly measures,” warns López-Goñi. At the second, solely Spain, Italy and France have carried out controls on passengers from China. But the EU as such doesn’t think about them obligatory. The ECDC issued a press release a couple of days in the past, describing it as an “unfounded” step, because of the excessive ranges of immunity we now have within the EU.

“Given the elevated inhabitants immunity within the EU/EEA, in addition to the pre-emergence and post-substitution of variants at present circulating in China by different omicron sub-lineages within the EU/EEA, it’s not anticipated that a rise in instances in China have an effect on the epidemiological state of affairs of COVID-19 within the EU/EEA,” the assertion learn.

The European physique opts for “energetic surveillance” of the state of affairs. “ECDC is carefully monitoring the state of affairs in China via epidemiological intelligence and is in common contact with the Chinese well being authorities and the primary facilities for management and prevention world wide, in addition to with the WHO.” Quique Bassat warned it clearly, a couple of days in the past: “The virus can return to us at any time, not solely from China”.